منابع مشابه
Whole Genome Complete Resequencing of Bacillus subtilis Natto by Combining Long Reads with High-Quality Short Reads
De novo microbial genome sequencing reached a turning point with third-generation sequencing (TGS) platforms, and several microbial genomes have been improved by TGS long reads. Bacillus subtilis natto is closely related to the laboratory standard strain B. subtilis Marburg 168, and it has a function in the production of the traditional Japanese fermented food "natto." The B. subtilis natto BES...
متن کاملCoLoRMap: Correcting Long Reads by Mapping short reads
MOTIVATION Second generation sequencing technologies paved the way to an exceptional increase in the number of sequenced genomes, both prokaryotic and eukaryotic. However, short reads are difficult to assemble and often lead to highly fragmented assemblies. The recent developments in long reads sequencing methods offer a promising way to address this issue. However, so far long reads are charac...
متن کاملRAMICS: trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA
The challenge presented by high-throughput sequencing necessitates the development of novel tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly to large genomes, rather than generating highly accurate alignments in coding regions. Such approaches are, thus, unsuited for applications such as amplicon-based analysis and t...
متن کاملA Mathematician Reads
New York University mathematical physicist Alan Sokal published in the postmodern humanities journal Social Text a parody entitled “Transgressing the Boundaries: Toward a Transformative Hermeneutics of Quantum Gravity” [1]. His point in doing so was to test whether the field of “cultural studies of science” was seriously lacking in “intellectual standards”. His article is nonsense from start to...
متن کاملRadiology double reads.
To cite: Sahni VA, Khorasani R. BMJ Qual Saf 2016;25:569–571. Diagnostic errors in radiology reports can result in patient harm, lead to unnecessary additional testing or interventions, or otherwise diminish the quality of care delivery. 2 In this issue, Lauritzen et al retrospectively evaluated the impact of a quality assurance process using double reads on changes made to abdominal CT reports...
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ژورنال
عنوان ژورنال: Nature
سال: 2010
ISSN: 0028-0836,1476-4687
DOI: 10.1038/463034b